CRISPR immunity relies on the consecutive binding and degradation of negatively supercoiled invader DNA by Cascade and Cas3

The prokaryotic CRISPR/Cas immune system is based on genomic loci that contain incorporated sequence tags from viruses and plasmids. Using small guide RNA molecules, these sequences act as a memory to reject returning invaders. Both the Cascade ribonucleoprotein complex and the Cas3 nuclease/helicas...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Westra, Edze R., van Erp, Paul B. G., Künne, Tim, Wong, Shi Pey, Staals, Raymond H. J., Seegers, Christel L. C., Bollen, Sander, Jore, Matthijs M., Semenova, Ekaterina, Severinov, Konstantin, de Vos, Willem M., Dame, Remus T., de Vries, Renko, Brouns, Stan J. J., van der Oost, John
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372689/
https://ncbi.nlm.nih.gov/pubmed/22521689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.03.018
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados