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RNA in Defense: CRISPRs Protect Prokaryotes against Mobile Genetic Elements
The CRISPR/Cas system in prokaryotes provides resistance against invading viruses and plasmids. Three distinct stages in the mechanism can be recognized. Initially, fragments of invader DNA are integrated as new spacers into the repetitive CRISPR locus. Subsequently, the CRISPR is transcribed and th...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3367551/ https://ncbi.nlm.nih.gov/pubmed/21441598 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a003657 |
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