Discovery of multiple anti-CRISPRs highlights anti-defense gene clustering in mobile genetic elements

Many prokaryotes employ CRISPR–Cas systems to combat invading mobile genetic elements (MGEs). In response, some MGEs have developed strategies to bypass immunity, including anti-CRISPR (Acr) proteins; yet the diversity, distribution and spectrum of activity of this immune evasion strategy remain lar...

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Bibliografische gegevens
Gepubliceerd in:Nat Commun
Hoofdauteurs: Pinilla-Redondo, Rafael, Shehreen, Saadlee, Marino, Nicole D., Fagerlund, Robert D., Brown, Chris M., Sørensen, Søren J., Fineran, Peter C., Bondy-Denomy, Joseph
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7648647/
https://ncbi.nlm.nih.gov/pubmed/33159058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19415-3
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