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Structures and Strategies of Anti-CRISPR Mediated Immune Suppression

Nearly fifty protein families have been identified that inhibit CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats)-Cas mediated adaptive immune systems. Here, we analyze the available anti-CRISPR (Acr) structures and describe common themes and unique mechanisms of stoichiometric and...

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Detalhes bibliográficos
Publicado no:Annu Rev Microbiol
Main Authors: Wiegand, Tanner, Karambelkar, Shweta, Bondy-Denomy, Joseph, Wiedenheft, Blake
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7712631/
https://ncbi.nlm.nih.gov/pubmed/32503371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-micro-020518-120107
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