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Prokaryotic homologs of Argonaute proteins are predicted to function as key components of a novel system of defense against mobile genetic elements

BACKGROUND: In eukaryotes, RNA interference (RNAi) is a major mechanism of defense against viruses and transposable elements as well of regulating translation of endogenous mRNAs. The RNAi systems recognize the target RNA molecules via small guide RNAs that are completely or partially complementary...

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Detalhes bibliográficos
Main Authors: Makarova, Kira S, Wolf, Yuri I, van der Oost, John, Koonin, Eugene V
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743648/
https://ncbi.nlm.nih.gov/pubmed/19706170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-6150-4-29
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