Evolutionary and functional classification of the CARF domain superfamily, key sensors in prokaryotic antivirus defense

CRISPR-associated Rossmann Fold (CARF) and SMODS-associated and fused to various effector domains (SAVED) are key components of cyclic oligonucleotide-based antiphage signaling systems (CBASS) that sense cyclic oligonucleotides and transmit the signal to an effector inducing cell dormancy or death....

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Makarova, Kira S, Timinskas, Albertas, Wolf, Yuri I, Gussow, Ayal B, Siksnys, Virginijus, Venclovas, Česlovas, Koonin, Eugene V
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
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Survey and Summary
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7498327/
https://ncbi.nlm.nih.gov/pubmed/32735657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa635
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