Evolutionary and functional classification of the CARF domain superfamily, key sensors in prokaryotic antivirus defense

CRISPR-associated Rossmann Fold (CARF) and SMODS-associated and fused to various effector domains (SAVED) are key components of cyclic oligonucleotide-based antiphage signaling systems (CBASS) that sense cyclic oligonucleotides and transmit the signal to an effector inducing cell dormancy or death....

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Enregistré dans:
Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Makarova, Kira S, Timinskas, Albertas, Wolf, Yuri I, Gussow, Ayal B, Siksnys, Virginijus, Venclovas, Česlovas, Koonin, Eugene V
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2020
Sujets:
Survey and Summary
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7498327/
https://ncbi.nlm.nih.gov/pubmed/32735657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa635
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