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Small CRISPR RNAs Guide Antiviral Defense in Prokaryotes
Prokaryotes acquire virus resistance by integrating short fragments of viral nucleic acid into clusters of regularly interspaced short palindromic repeats (CRISPRs). Here we show how virus-derived sequences contained in CRISPRs are used by CRISPR-associated (Cas) proteins from the host to mediate an...
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| Vydáno v: | Science |
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| Hlavní autoři: | , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2008
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5898235/ https://ncbi.nlm.nih.gov/pubmed/18703739 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1159689 |
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