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Probing hyper-negatively supercoiled mini-circles with nucleases and DNA binding proteins
It is well accepted that the introduction of negative supercoils locally unwinds the DNA double helix, influencing thus the activity of proteins. Despite the use of recent methods of molecular dynamics simulations to model the DNA supercoiling-induced DNA deformation, the precise extent and location...
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| Publicado no: | PLoS One |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6095550/ https://ncbi.nlm.nih.gov/pubmed/30114256 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0202138 |
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