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Preferential binding of E.coli histone-like protein HU alpha to negatively supercoiled DNA.
Binding specificity of histone-like HU alpha protein to supercoiled DNA was examined by gel retardation assay and chemical probing with OsO4. The latter method was proved to be a unique means for detecting torsional tension restrained in supercoiled plasmid in the presence of HU alpha. It was shown...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
1992
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC312237/ https://ncbi.nlm.nih.gov/pubmed/1579448 |
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