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CRISPR-DO for genome-wide CRISPR design and optimization
Motivation: Despite the growing popularity in using CRISPR/Cas9 technology for genome editing and gene knockout, its performance still relies on well-designed single guide RNAs (sgRNA). In this study, we propose a web application for the Design and Optimization (CRISPR-DO) of guide sequences that ta...
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| Veröffentlicht in: | Bioinformatics |
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| Hauptverfasser: | , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6095119/ https://ncbi.nlm.nih.gov/pubmed/27402906 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw476 |
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