CRISPR-DO for genome-wide CRISPR design and optimization

Motivation: Despite the growing popularity in using CRISPR/Cas9 technology for genome editing and gene knockout, its performance still relies on well-designed single guide RNAs (sgRNA). In this study, we propose a web application for the Design and Optimization (CRISPR-DO) of guide sequences that ta...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Ma, Jian, Köster, Johannes, Qin, Qian, Hu, Shengen, Li, Wei, Chen, Chenhao, Cao, Qingyi, Wang, Jinzeng, Mei, Shenglin, Liu, Qi, Xu, Han, Liu, Xiaole Shirley
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Applications Notes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6095119/
https://ncbi.nlm.nih.gov/pubmed/27402906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw476
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