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CRISPR-FOCUS: A web server for designing focused CRISPR screening experiments

The recently developed CRISPR screen technology, based on the CRISPR/Cas9 genome editing system, enables genome-wide interrogation of gene functions in an efficient and cost-effective manner. Although many computational algorithms and web servers have been developed to design single-guide RNAs (sgRN...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Cao, Qingyi, Ma, Jian, Chen, Chen-Hao, Xu, Han, Chen, Zhi, Li, Wei, Liu, X. Shirley
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584922/
https://ncbi.nlm.nih.gov/pubmed/28873439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0184281
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