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CRISPR-ERA: a comprehensive design tool for CRISPR-mediated gene editing, repression and activation

Summary: The CRISPR/Cas9 system was recently developed as a powerful and flexible technology for targeted genome engineering, including genome editing (altering the genetic sequence) and gene regulation (without altering the genetic sequence). These applications require the design of single guide RN...

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Podrobná bibliografie
Vydáno v:Bioinformatics
Hlavní autoři: Liu, Honglei, Wei, Zheng, Dominguez, Antonia, Li, Yanda, Wang, Xiaowo, Qi, Lei S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4757951/
https://ncbi.nlm.nih.gov/pubmed/26209430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btv423
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