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CRISPR-ERA: a comprehensive design tool for CRISPR-mediated gene editing, repression and activation

Summary: The CRISPR/Cas9 system was recently developed as a powerful and flexible technology for targeted genome engineering, including genome editing (altering the genetic sequence) and gene regulation (without altering the genetic sequence). These applications require the design of single guide RN...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Liu, Honglei, Wei, Zheng, Dominguez, Antonia, Li, Yanda, Wang, Xiaowo, Qi, Lei S.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4757951/
https://ncbi.nlm.nih.gov/pubmed/26209430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btv423
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