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CRISPR-ERA: a comprehensive design tool for CRISPR-mediated gene editing, repression and activation

Summary: The CRISPR/Cas9 system was recently developed as a powerful and flexible technology for targeted genome engineering, including genome editing (altering the genetic sequence) and gene regulation (without altering the genetic sequence). These applications require the design of single guide RN...

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Bibliographic Details
Published in:Bioinformatics
Main Authors: Liu, Honglei, Wei, Zheng, Dominguez, Antonia, Li, Yanda, Wang, Xiaowo, Qi, Lei S.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4757951/
https://ncbi.nlm.nih.gov/pubmed/26209430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btv423
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