Metabolism of primaquine in normal human volunteers: investigation of phase I and phase II metabolites from plasma and urine using ultra-high performance liquid chromatography-quadrupole time-of-flight mass spectrometry

BACKGROUND: Primaquine (PQ), an 8-aminoquinoline, is the only drug approved by the United States Food and Drug Administration for radical cure and prevention of relapse in Plasmodium vivax infections. Knowledge of the metabolism of PQ is critical for understanding the therapeutic efficacy and hemoly...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Malar J
Κύριοι συγγραφείς: Avula, Bharathi, Tekwani, Babu L., Chaurasiya, Narayan D., Fasinu, Pius, Dhammika Nanayakkara, N. P., Bhandara Herath, H. M. T., Wang, Yan-Hong, Bae, Ji-Yeong, Khan, Shabana I., Elsohly, Mahmoud A., McChesney, James D., Zimmerman, Peter A., Khan, Ikhlas A., Walker, Larry A.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: BioMed Central 2018
Θέματα:
Research
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6090659/
https://ncbi.nlm.nih.gov/pubmed/30103751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-018-2433-z
Ετικέτες: Προσθήκη ετικέτας
Δεν υπάρχουν, Καταχωρήστε ετικέτα πρώτοι!

Παρόμοια τεκμήρια