Pathway-specific inhibition of primaquine metabolism by chloroquine/quinine

BACKGROUND: There has been some evidence to suggest that the addition of chloroquine (CQ) or quinine (QN) to 8-aminoquinoline (8-AQ) treatment regimens may increase the therapeutic efficacy of the 8-AQ and simultaneously mitigate against its haemolytic toxicity. However, both CQ and QN are considere...

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Detalhes bibliográficos
Publicado no:Malar J
Main Authors: Fasinu, Pius S., Tekwani, Babu L., Avula, Bharathi, Chaurasiya, Narayan D., Nanayakkara, N. P. Dhammika, Wang, Yan-Hong, Khan, Ikhlas A., Walker, Larry A.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5020452/
https://ncbi.nlm.nih.gov/pubmed/27618912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-016-1509-x
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