Pathway-specific inhibition of primaquine metabolism by chloroquine/quinine

BACKGROUND: There has been some evidence to suggest that the addition of chloroquine (CQ) or quinine (QN) to 8-aminoquinoline (8-AQ) treatment regimens may increase the therapeutic efficacy of the 8-AQ and simultaneously mitigate against its haemolytic toxicity. However, both CQ and QN are considere...

Full description

Saved in:
Bibliographic Details
Published in:Malar J
Main Authors: Fasinu, Pius S., Tekwani, Babu L., Avula, Bharathi, Chaurasiya, Narayan D., Nanayakkara, N. P. Dhammika, Wang, Yan-Hong, Khan, Ikhlas A., Walker, Larry A.
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5020452/
https://ncbi.nlm.nih.gov/pubmed/27618912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-016-1509-x
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items