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Measuring NDC80 binding reveals the molecular basis of tension-dependent kinetochore-microtubule attachments
Proper kinetochore-microtubule attachments, mediated by the NDC80 complex, are required for error-free chromosome segregation. Erroneous attachments are corrected by the tension dependence of kinetochore-microtubule interactions. Here, we present a method, based on fluorescence lifetime imaging micr...
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| Опубликовано в: : | eLife |
|---|---|
| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
eLife Sciences Publications, Ltd
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6089600/ https://ncbi.nlm.nih.gov/pubmed/30044223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.36392 |
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