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Implications for Kinetochore-Microtubule Attachment from the Structure of an Engineered Ndc80 Complex

Kinetochores are proteinaceous assemblies that mediate the interaction of chromosomes with the mitotic spindle. The 180 kDa Ndc80 complex is a direct point of contact between kinetochores and microtubules. Its four subunits contain coiled coils and form an elongated rod structure with functional glo...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Ciferri, Claudio, Pasqualato, Sebastiano, Screpanti, Emanuela, Varetti, Gianluca, Santaguida, Stefano, Reis, Gabriel Dos, Maiolica, Alessio, Polka, Jessica, De Luca, Jennifer G., De Wulf, Peter, Salek, Mogjiborahman, Rappsilber, Juri, Moores, Carolyn A., Salmon, Edward D., Musacchio, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4754795/
https://ncbi.nlm.nih.gov/pubmed/18455984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.03.020
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