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The Ndc80 kinetochore complex forms oligomeric arrays along microtubules

The Ndc80 complex is a key site of regulated kinetochore-microtubule attachment, but the molecular mechanism underlying its function remains unknown. Here we present a subnanometer resolution cryo-electron microscopy reconstruction of the human Ndc80 complex bound to microtubules, sufficient for pre...

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Detalhes bibliográficos
Main Authors: Alushin, Gregory M., Ramey, Vincent H., Pasqualato, Sebastiano, Ball, David A., Grigorieff, Nikolaus, Musacchio, Andrea, Nogales, Eva
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2957311/
https://ncbi.nlm.nih.gov/pubmed/20944740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09423
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