Measuring NDC80 binding reveals the molecular basis of tension-dependent kinetochore-microtubule attachments

Proper kinetochore-microtubule attachments, mediated by the NDC80 complex, are required for error-free chromosome segregation. Erroneous attachments are corrected by the tension dependence of kinetochore-microtubule interactions. Here, we present a method, based on fluorescence lifetime imaging micr...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:eLife
Main Authors: Yoo, Tae Yeon, Choi, Jeong-Mo, Conway, William, Yu, Che-Hang, Pappu, Rohit V, Needleman, Daniel J
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2018
Teme:
Cell Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6089600/
https://ncbi.nlm.nih.gov/pubmed/30044223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.36392
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki