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Dephosphorylation of the Ndc80 Tail Stabilizes Kinetochore-Microtubule Attachments via the Ska Complex

During cell division, genome inheritance is orchestrated by microtubule attachments formed at kinetochores of mitotic chromosomes. The primary microtubule coupler at the kinetochore, the Ndc80 complex, is regulated by Aurora kinase phosphorylation of its N-terminal tail. Dephosphorylation is propose...

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Detalhes bibliográficos
Publicado no:Dev Cell
Main Authors: Cheerambathur, Dhanya K., Prevo, Bram, Hattersley, Neil, Lewellyn, Lindsay, Corbett, Kevin D., Oegema, Karen, Desai, Arshad
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5572820/
https://ncbi.nlm.nih.gov/pubmed/28535376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2017.04.013
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