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Dephosphorylation of the Ndc80 Tail Stabilizes Kinetochore-Microtubule Attachments via the Ska Complex

During cell division, genome inheritance is orchestrated by microtubule attachments formed at kinetochores of mitotic chromosomes. The primary microtubule coupler at the kinetochore, the Ndc80 complex, is regulated by Aurora kinase phosphorylation of its N-terminal tail. Dephosphorylation is propose...

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Dettagli Bibliografici
Pubblicato in:Dev Cell
Autori principali: Cheerambathur, Dhanya K., Prevo, Bram, Hattersley, Neil, Lewellyn, Lindsay, Corbett, Kevin D., Oegema, Karen, Desai, Arshad
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5572820/
https://ncbi.nlm.nih.gov/pubmed/28535376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2017.04.013
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