Dephosphorylation of the Ndc80 Tail Stabilizes Kinetochore-Microtubule Attachments via the Ska Complex

During cell division, genome inheritance is orchestrated by microtubule attachments formed at kinetochores of mitotic chromosomes. The primary microtubule coupler at the kinetochore, the Ndc80 complex, is regulated by Aurora kinase phosphorylation of its N-terminal tail. Dephosphorylation is propose...

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Bibliographic Details
Published in:Dev Cell
Main Authors: Cheerambathur, Dhanya K., Prevo, Bram, Hattersley, Neil, Lewellyn, Lindsay, Corbett, Kevin D., Oegema, Karen, Desai, Arshad
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5572820/
https://ncbi.nlm.nih.gov/pubmed/28535376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2017.04.013
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