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Antagonism between the dynein and Ndc80 complexes at kinetochores controls the stability of kinetochore–microtubule attachments during mitosis
Chromosome alignment and segregation during mitosis require kinetochore–microtubule (kMT) attachments that are mediated by the molecular motor dynein and the kMT-binding complex Ndc80. The Rod–ZW10–Zwilch (RZZ) complex is central to this coordination as it has an important role in dynein recruitment...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5912454/ https://ncbi.nlm.nih.gov/pubmed/29475948 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.001699 |
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