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Antagonism between the dynein and Ndc80 complexes at kinetochores controls the stability of kinetochore–microtubule attachments during mitosis

Chromosome alignment and segregation during mitosis require kinetochore–microtubule (kMT) attachments that are mediated by the molecular motor dynein and the kMT-binding complex Ndc80. The Rod–ZW10–Zwilch (RZZ) complex is central to this coordination as it has an important role in dynein recruitment...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Amin, Mohammed A., McKenney, Richard J., Varma, Dileep
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5912454/
https://ncbi.nlm.nih.gov/pubmed/29475948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.001699
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