טוען...
Replication Fork Reversal during DNA Interstrand Crosslink Repair Requires CMG Unloading
DNA interstrand crosslinks (ICLs) are extremely cytotoxic, but the mechanism of their repair remains incompletely understood. Using Xenopus egg extracts, we previously showed that repair of a cisplatin ICL is triggered when two replication forks converge on the lesion. After CDC45/MCM2-7/GINS (CMG)...
שמור ב:
| הוצא לאור ב: | Cell Rep |
|---|---|
| Main Authors: | , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2018
|
| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6086610/ https://ncbi.nlm.nih.gov/pubmed/29924986 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.05.061 |
| תגים: |
הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!
|