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Specificity in intracellular protein aggregation and inclusion body formation

Protein aggregation is widely considered to be a nonspecific coalescence of misfolded proteins, driven by interactions between solvent-exposed hydrophobic surfaces that are normally buried within a protein's interior. Accordingly, abnormal interactions between misfolded proteins with normal cel...

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Autors principals: Rajan, Rahul S., Illing, Michelle E., Bence, Neil F., Kopito, Ron R.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC60824/
https://ncbi.nlm.nih.gov/pubmed/11687604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.181479798
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