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Protein misfolding specifies recruitment to cytoplasmic inclusion bodies
Inclusion bodies (IBs) containing aggregated disease-associated proteins and polyubiquitin (poly-Ub) conjugates are universal histopathological features of neurodegenerative diseases. Ub has been proposed to target proteins to IBs for degradation via autophagy, but the mechanisms that govern recruit...
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| Pubblicato in: | J Cell Biol |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Rockefeller University Press
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5084276/ https://ncbi.nlm.nih.gov/pubmed/27114501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201511024 |
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