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Protein misfolding specifies recruitment to cytoplasmic inclusion bodies
Inclusion bodies (IBs) containing aggregated disease-associated proteins and polyubiquitin (poly-Ub) conjugates are universal histopathological features of neurodegenerative diseases. Ub has been proposed to target proteins to IBs for degradation via autophagy, but the mechanisms that govern recruit...
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| 出版年: | J Cell Biol |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5084276/ https://ncbi.nlm.nih.gov/pubmed/27114501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201511024 |
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