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Kinetics of Inclusion Body Formation and Its Correlation with the Characteristics of Protein Aggregates in Escherichia coli

The objective of the research was to understand the structural determinants governing protein aggregation into inclusion bodies during expression of recombinant proteins in Escherichia coli. Recombinant human growth hormone (hGH) and asparaginase were expressed as inclusion bodies in E.coli and the...

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Detalhes bibliográficos
Main Authors: Upadhyay, Arun K., Murmu, Aruna, Singh, Anupam, Panda, Amulya K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315509/
https://ncbi.nlm.nih.gov/pubmed/22479486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033951
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