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Structure-Function Relationship of Inclusion Bodies of a Multimeric Protein

High level expression of recombinant proteins in bacteria often results in their aggregation into inclusion bodies. Formation of inclusion bodies poses a major bottleneck in high-throughput recovery of recombinant protein. These aggregates have amyloid-like nature and can retain biological activity....

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Détails bibliographiques
Publié dans:Front Microbiol
Auteurs principaux: Singh, Anupam, Upadhyay, Vaibhav, Singh, Akansha, Panda, Amulya K.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7225587/
https://ncbi.nlm.nih.gov/pubmed/32457730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.00876
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