Chargement en cours...
HRD4/NPL4 Is Required for the Proteasomal Processing of Ubiquitinated ER Proteins
We isolated a temperature-sensitive mutant, hrd4–1, deficient in ER-associated degradation (ERAD). The HRD4 gene was identical to NPL4, a gene previously implicated in nuclear transport. Using a diverse set of substrates and direct ubiquitination assays, our analysis revealed that HRD4/NPL4 is requi...
Enregistré dans:
| Auteurs principaux: | , , , , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The American Society for Cell Biology
2001
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC60780/ https://ncbi.nlm.nih.gov/pubmed/11739805 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|