Conservation of oncofetal antigens on human embryonic stem cells enables discovery of monoclonal antibodies against cancer

Monoclonal antibodies (mAbs) are used as targeted therapies against cancers. These mAbs kill cancer cells via various mechanisms of actions. In this study, human embryonic stem cells (hESCs) was used as the immunogen to generate a panel of antibodies. From this panel of mAbs, A19 was found to bind b...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Tan, Heng Liang, Yong, Charlene, Tan, Bao Zhu, Fong, Wey Jia, Padmanabhan, Jayanthi, Chin, Angela, Ding, Vanessa, Lau, Ally, Zheng, Lu, Bi, Xuezhi, Yang, Yuansheng, Choo, Andre
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2018
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072701/
https://ncbi.nlm.nih.gov/pubmed/30072783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-30070-z
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items