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Conservation of oncofetal antigens on human embryonic stem cells enables discovery of monoclonal antibodies against cancer
Monoclonal antibodies (mAbs) are used as targeted therapies against cancers. These mAbs kill cancer cells via various mechanisms of actions. In this study, human embryonic stem cells (hESCs) was used as the immunogen to generate a panel of antibodies. From this panel of mAbs, A19 was found to bind b...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6072701/ https://ncbi.nlm.nih.gov/pubmed/30072783 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-30070-z |
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