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Excess reactive oxygen species production mediates monoclonal antibody-induced human embryonic stem cell death via oncosis

Antibody-mediated cell killing has significantly facilitated the elimination of undesired cells in therapeutic applications. Besides the well-known Fc-dependent mechanisms, pathways of antibody-induced apoptosis were also extensively studied. However, with fewer studies reporting the ability of anti...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Zheng, Ji Yun, Tan, Heng Liang, Matsudaira, Paul Thomas, Choo, Andre
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5344215/
https://ncbi.nlm.nih.gov/pubmed/28106884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2016.164
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