Llwytho...

In vivo surveillance and elimination of teratoma‐forming human embryonic stem cells with monoclonal antibody 2448 targeting annexin A2

This study describes the use of a previously reported chimerised monoclonal antibody (mAb), ch2448, to kill human embryonic stem cells (hESCs) in vivo and prevent or delay the formation of teratomas. ch2448 was raised against hESCs and was previously shown to effectively kill ovarian and breast canc...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biotechnol Bioeng
Prif Awduron: Tan, Heng Liang, Tan, Bao Zhu, Goh, Winfred Xi Tai, Cua, Simeon, Choo, Andre
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6790577/
https://ncbi.nlm.nih.gov/pubmed/31388993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.27135
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