Prospective randomized biomarker study of metformin and lifestyle intervention for prevention in obese women at increased risk for endometrial cancer

Obesity increases risk of endometrial cancer through dysregulation of estrogen and insulin signaling. The primary aim of this study was to evaluate the impact of metformin or lifestyle intervention on endometrial proliferation in postmenopausal obese women. Secondary aims included evaluating obesity...

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Udgivet i:Cancer Prev Res (Phila)
Main Authors: Yates, Melinda S., Coletta, Adriana M., Zhang, Qian, Schmandt, Rosemarie E., Medepalli, Meena, Nebgen, Denise, Soletsky, Beth, Milbourne, Andrea, Levy, Erma, Fellman, Bryan, Urbauer, Diana, Yuan, Ying, Broaddus, Russell R., Basen-Engquist, Karen, Lu, Karen
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072574/
https://ncbi.nlm.nih.gov/pubmed/29716897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-17-0398
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