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Inhibition of O-GlcNAc transferase (OGT) by peptidic hybrids
O-GlcNAc transferase (OGT) attaches a GlcNAc moiety on specific substrate proteins using UDP-GlcNAc as the sugar donor. This modification can alter protein function by regulating cellular signaling and transcription pathways in response to altered nutrient availability and stress. Specific inhibitor...
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| Publicado en: | Medchemcomm |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Royal Society of Chemistry
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6072325/ https://ncbi.nlm.nih.gov/pubmed/30108977 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8md00115d |
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