Activity Based High-Throughput Screening for Novel O-GlcNAc Transferase Substrates Using a Dynamic Peptide Microarray

O-GlcNAcylation is a reversible and dynamic protein post-translational modification in mammalian cells. The O-GlcNAc cycle is catalyzed by O-GlcNAc transferase (OGT) and O-GlcNAcase (OGA). O-GlcNAcylation plays important role in many vital cellular events including transcription, cell cycle regulati...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Shi, Jie, Sharif, Suhela, Ruijtenbeek, Rob, Pieters, Roland J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2016
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4784888/
https://ncbi.nlm.nih.gov/pubmed/26960196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151085
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