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Structure of human O-GlcNAc transferase and its complex with a peptide substrate
O-GlcNAc transferase (OGT) is an essential mammalian enzyme that couples metabolic status to the regulation of a wide variety of cellular signaling pathways by acting as a nutrient sensor1. OGT catalyzes the transfer of N-acetyl-glucosamine from UDP-GlcNAc to serines and threonines of cytoplasmic, n...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3064491/ https://ncbi.nlm.nih.gov/pubmed/21240259 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09638 |
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