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HCF-1 is cleaved in the active site of O-GlcNAc transferase
Host Cell Factor-1 (HCF-1), a transcriptional co-regulator of human cell-cycle progression, undergoes proteolytic maturation in which any of six repeated sequences is cleaved by the nutrient-responsive glycosyltransferase, O-linked N-acetylglucosamine (O-GlcNAc) transferase (OGT). We report that the...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3930058/ https://ncbi.nlm.nih.gov/pubmed/24311690 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1243990 |
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