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Electrophilic probes for deciphering substrate recognition by O-GlcNAc transferase
O-linked β-N-acetylglucosamine (O-GlcNAc) transferase (OGT) is an essential human glycosyltransferase that adds O-GlcNAc modifications on numerous proteins. However, little is known about how OGT recognizes various protein substrates. Here we report GlcNAc electrophilic probes (GEPs) to expedite the...
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| Publicado no: | Nat Chem Biol |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5698155/ https://ncbi.nlm.nih.gov/pubmed/29058723 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2494 |
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