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Electrophilic probes for deciphering substrate recognition by O-GlcNAc transferase
O-linked β-N-acetylglucosamine (O-GlcNAc) transferase (OGT) is an essential human glycosyltransferase that adds O-GlcNAc modifications on numerous proteins. However, little is known about how OGT recognizes various protein substrates. Here we report GlcNAc electrophilic probes (GEPs) to expedite the...
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| 出版年: | Nat Chem Biol |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5698155/ https://ncbi.nlm.nih.gov/pubmed/29058723 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2494 |
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