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Elucidating the Protein Substrate Recognition of O-GlcNAc Transferase (OGT) Toward O-GlcNAcase (OGA) Using a GlcNAc Electrophilic Probe
The essential human O-linked β-N-acetylglucosamine (O-GlcNAc) transferase (OGT) is the sole enzyme responsible for modifying thousands of intracellular proteins with the monosaccharide O-GlcNAc. This unique modification plays crucial roles in human health and disease, but the substrate recognition o...
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| Udgivet i: | Int J Biol Macromol |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7856287/ https://ncbi.nlm.nih.gov/pubmed/33333092 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijbiomac.2020.12.078 |
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