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Design, synthesis, and biological evaluation of new thiazolo[5,4-d]pyrimidine derivatives as potent antiproliferative agents

A series of thiazolo[5,4-d]pyrimidine derivatives were synthesized and evaluated for their antiproliferative activities against several human cancer cell lines. Structure–activity relationship studies were carried out, showing that most of the target compounds had good inhibition against the tested...

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Détails bibliographiques
Publié dans:Medchemcomm
Auteurs principaux: Li, Zhong-Hua, Liu, Xue-Qi, Geng, Peng-Fei, Ma, Jin-Lian, Zhao, Tao-Qian, Wei, Hao-Ming, Yu, Bin, Liu, Hong-Min
Format: Artigo
Langue:Inglês
Publié: Royal Society of Chemistry 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6071795/
https://ncbi.nlm.nih.gov/pubmed/30108876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7md00165g
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