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Benign Synthesis of Thiazolo-androstenone Derivatives as Potent Anticancer Agents

An unprecedented reaction of thiourea derivatives with 6β-bromoandrostenedione has been discovered for the formation of aminothiazolo-androstenones via a simple, safer, cascade protocol that enables the syntheses of novel molecules by using readily available reagents. The reaction mechanism of produ...

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Detalhes bibliográficos
Publicado no:Org Lett
Main Authors: Ali, Mohamad Akbar, Okolo, ChrisTina, Alsharif, Zakeyah A., Whitt, Jedidiah, Chambers, Steven A., Varma, Rajender S., Alam, Mohammad A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6441354/
https://ncbi.nlm.nih.gov/pubmed/30204455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.8b02587
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