Molecular docking, synthesis and biological significance of pyrimidine analogues as prospective antimicrobial and antiproliferative agents

Pyrimidine nucleus is a significant pharmacophore that exhibited excellent pharmacological activities. A series of pyrimidine scaffolds was synthesized and its chemical structures were confirmed by physicochemical and spectral analysis. The synthesized compounds were evaluated for their antimicrobia...

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Bibliographische Detailangaben
Veröffentlicht in:BMC Chem
Hauptverfasser: Kumar, Sanjiv, Kaushik, Archana, Narasimhan, Balasubramanian, Shah, Syed Adnan Ali, Lim, Siong Meng, Ramasamy, Kalavathy, Mani, Vasudevan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer International Publishing 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6661814/
https://ncbi.nlm.nih.gov/pubmed/31384832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13065-019-0601-z
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