Design, Synthesis, and Biological Evaluation of Artemisinin-Indoloquinoline Hybrids as Potent Antiproliferative Agents

A series of artemisinin-indoloquinoline hybrids were designed and synthesized in an attempt to develop potent and selective anti-tumor agents. Compounds 7a–7f, 8 and 9 were prepared and characterized. Their antiproliferative activities against MV4-11, HCT-116, A549, and BALB/3T3 cell lines in vitro...

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Bibliographic Details
Published in:Molecules
Main Authors: Wang, Li, Świtalska, Marta, Wang, Ning, Du, Zhen-Jun, Fukumoto, Yuta, Diep, Nguyen Kim, Kiguchi, Ryo, Nokami, Junzo, Wietrzyk, Joanna, Inokuchi, Tsutomu
Format: Artigo
Language:Inglês
Published: MDPI 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6271626/
https://ncbi.nlm.nih.gov/pubmed/25412047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules191119021
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