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2-Arylaminobenzothiazole-arylpropenone conjugates as tubulin polymerization inhibitors

A new series of 2-arylaminobenzothiazole-arylpropenone conjugates 5–6(a–r) was designed, synthesized and investigated for their cytotoxic potency against the various human cancer cell lines. Most of these conjugates exhibited cytotoxic activity and inhibited in vitro tubulin polymerization effective...

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Détails bibliographiques
Publié dans:Medchemcomm
Auteurs principaux: Subba Rao, A. V., Rao, Bala Bhaskara, Sunkari, Satish, Shaik, Siddiq Pasha, Shaik, Bajee, Kamal, Ahmed
Format: Artigo
Langue:Inglês
Publié: Royal Society of Chemistry 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6071745/
https://ncbi.nlm.nih.gov/pubmed/30108808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6md00562d
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