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Discovery of Biarylaminoquinazolines as Novel Tubulin Polymerization Inhibitors
[Image: see text] Cell cycle experiments with our previously reported 4-biphenylaminoquinazoline (1–3) multityrosine kinase inhibitors revealed an activity profile resembling that of known tubulin polymerization inhibitors. Novel 4-biarylaminoquinazoline analogues of compound 2 were synthesized and...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4086859/ https://ncbi.nlm.nih.gov/pubmed/24801610 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm500034j |
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