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INTERACTION OF DIAZONAMIDE A WITH TUBULIN

[(3)H]Diazonamide A ([(3)H]DZA), prepared from the natural product isolated from Diazona angulata, bound to tubulin in larger aberrant assembly products (> 500 kDa by sizing HPLC) but not to the α,β-tubulin heterodimer. The binding reaction was rapid, but stoichiometry was low. Stoichiometry was...

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Detalhes bibliográficos
Publicado no:Arch Biochem Biophys
Main Authors: Bai, Ruoli, Cruz-Monserrate, Zobeida, Fenical, William, Pettit, George R., Hamel, Ernest
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7047882/
https://ncbi.nlm.nih.gov/pubmed/31830440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2019.108217
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