Interactions of Halichondrin B and Eribulin with Tubulin

[Image: see text] Compounds that modulate microtubule dynamics include highly effective anticancer drugs, leading to continuing efforts to identify new agents and improve the activity of established ones. Here, we demonstrate that [(3)H]-labeled halichondrin B (HB), a complex, sponge-derived natural...

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Auteurs principaux: Bai, Ruoli, Nguyen, Tam Luong, Burnett, James C., Atasoylu, Onur, Munro, Murray H. G., Pettit, George R., Smith, Amos B., Gussio, Rick, Hamel, Ernest
Format: Artigo
Langue:Inglês
Publié: 2011
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130535/
https://ncbi.nlm.nih.gov/pubmed/21539396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ci200077t
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