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2-Arylaminobenzothiazole-arylpropenone conjugates as tubulin polymerization inhibitors

A new series of 2-arylaminobenzothiazole-arylpropenone conjugates 5–6(a–r) was designed, synthesized and investigated for their cytotoxic potency against the various human cancer cell lines. Most of these conjugates exhibited cytotoxic activity and inhibited in vitro tubulin polymerization effective...

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Bibliografiske detaljer
Udgivet i:Medchemcomm
Main Authors: Subba Rao, A. V., Rao, Bala Bhaskara, Sunkari, Satish, Shaik, Siddiq Pasha, Shaik, Bajee, Kamal, Ahmed
Format: Artigo
Sprog:Inglês
Udgivet: Royal Society of Chemistry 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6071745/
https://ncbi.nlm.nih.gov/pubmed/30108808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6md00562d
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