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2-Arylaminobenzothiazole-arylpropenone conjugates as tubulin polymerization inhibitors

A new series of 2-arylaminobenzothiazole-arylpropenone conjugates 5–6(a–r) was designed, synthesized and investigated for their cytotoxic potency against the various human cancer cell lines. Most of these conjugates exhibited cytotoxic activity and inhibited in vitro tubulin polymerization effective...

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Detalhes bibliográficos
Publicado no:Medchemcomm
Main Authors: Subba Rao, A. V., Rao, Bala Bhaskara, Sunkari, Satish, Shaik, Siddiq Pasha, Shaik, Bajee, Kamal, Ahmed
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6071745/
https://ncbi.nlm.nih.gov/pubmed/30108808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6md00562d
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